Extrachromosomal DNAs (ecDNAs) are a pervasive feature found in cancer and contain oncogenes and their corresponding regulatory elements.Their unique structural properties allow a rapid amplification of oncogenes and alter chromatin accessibility, leading to tumorigenesis and malignant development.The uneven segregation of ecDNA during Gift Card ce
Abstract Background Agastache rugosa (Fisch.& C.A.Mey.) Kuntze (Korean mint) is used to treat diverse types of human disorders in traditional medicine.In recent years, its non-fermented leaf extract (ARE) has been shown to possess protective properties against ultraviolet-B (UV-B) radiation-induced photooxidative stress.The present Dandelion Root w
In this paper, a new type of buckling-restrained brace characterized by a variable cross-section core (BRB-VCC) is proposed and investigated.The practical design equations of the BRB-VCC are derived based on mechanical and mathematical theories.Six specimens are designed and tested to clarify the mechanical behaviours of the BRB-VCC and to Collars
During the last decades, several windstorm series hit Europe leading to large aggregated losses.Such storm series are examples of serial Round Casserole clustering of extreme cyclones, presenting a considerable risk for the insurance industry.Clustering of events and return periods of storm series for Germany are quantified based on potential losse